Prevalence of prostate cancer (PCa) is the most commonly diagnosed cancer in men globally, with over 1.6 million cases. It has been observed to be significantly high among native African black men in the last four decades. Its occurrence was reported to have the highest mortality rate among men and was the leading cause of cancer deaths among men in many countries. Its incidence is associated with some risk factors such as age, family history and race. Descriptive cross-sectional approach was adopted. A total of (n=640) aged men were recruited from selected communities in Ibadan North East Local Government Area. An interviewer-administered questionnaire was used to obtain data from the study participants. Data was analyzed using IBM*SPSS version 21 for windows.

Results showed that the mean age of the respondents was 50.5±7.5years. About three hundred and fifty (54.7%) of the study participants had poor knowledge about PCa risk factors and three hundred and sixty-four (56.7%) had poor perception of the screening. Five hundred and thirty-four (83.6%) of the respondents were willing to be screened for PCa. Results also indicates that the relationship between willingness to be screened for PCa and perception about PCa screening test was not statistically significant (χ2=0.151, p=0.698). Findings indicate there was an association on monthly income (χ2=15.385) and ethnic groups (χ2= 17.168) on willingness to uptake prostate cancer screening test. Participants between ₦30,000 and ₦99,999 as monthly income were 3.4odds (almost four times) more likely to be willing to uptake PCa screening test than other categories (OR=3.417, CI=0.667, 17.501).