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International Journal of
Medical Science and Research
ARCHIVES
VOL. 6, ISSUE 2 (2024)
Prevalence of congenital heart disease in neonatal ICU in moderate high altitude
Authors
Bisht Dinesh, Negi Prakash Chand, Bhardwaj Parveen, Sood Mangla, Rana Jitender
Abstract

534 neonates with saturation less than 95 percent with Persistent oxygen dependency, murmur, tachypnea more than 55 per minute were taken for Echocardiography in Kamla Nehru Hospital, a branch of IGMC Shimla. The prevalence of CHD in NICU was 15 percent which simulated with prevalence described previously. Clinical tools were at par with echo study. 

Among Cyanotic CHD; TOF- 2 case, TGA- 1 case, DORV-1 case, Mitral Atresia -2 cases.

PPHN was seen in 250 cases. Among Acyanotic CHD, ASD-1 case, VSD- small-1 case, VSD Moderate size -1 case, Large VSD -2 cases, PDA- Large -31 cases, AVSD-1 case, Moderate MR -21 cases, Severe biventricular dysfunction-19 cases, Significant Biventricular hypertrophy-21 cases.

SHD was detected 2 -6 day of age with significant p value (0.004) as compared to Non SHD group. Oxygen saturation less than 95 percent was significantly associated with SHD with a significant p value (0.06).

Cyanotic CHD presented earlier than Acyanotic CHD with a significant p value (0.08). Higher maternal age showed significant correlation with Cyanotic CHD (p value - 0.04). Male babies had more cyanotic CHD than female babies (p value- 0.07)

Gestational age, birth weight, tachypnea, retraction, tachycardia, paternal age did not show any significance with acyanotic or cyanotic CHD.

On logistic regression analysis, for diagnosis of SHD, HR increase by 10 per minute, 1.78(1.07-2.96) P value=0.02, and detection of murmur 3.0(1.29-7.3),p value=0.01  showed highly  significant p values.

PPHN was seen in 50 percent of neonates. Sildenafil was started in neonates with Persistent oxygen dependency. The Hospital stay was reduced from 6 weeks to 3 weeks. The cause of Biventricular dysfunction was Birth asphyxia, HMD, Pneumonia with sepsis. The cause of Significant Mitral Regurgitation was LV dysfunction. The cause of Significant Biventricular hypertrophy was Gestational Diabetes and Inborn errors of metabolism.
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Pages:11-17
How to cite this article:
Bisht Dinesh, Negi Prakash Chand, Bhardwaj Parveen, Sood Mangla, Rana Jitender "Prevalence of congenital heart disease in neonatal ICU in moderate high altitude". International Journal of Medical Science and Research, Vol 6, Issue 2, 2024, Pages 11-17
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