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VOL. 6, ISSUE 2 (2024)
Efficacy test of Aloe Vera ethanol extract ointment (Aloe Barbadensis Milleer) On healing grade Ii Burns in Wistar Rats
Authors
Wu Pingdong, Liena
Abstract
Since ancient times, Indonesian people have
known and used medicinal plants, including aloe vera, as a solution to health
problems. Aloe vera proves effective in healing various wounds, including
burns, due to its essential nutritional content and ability to stimulate the
growth of skin tissue. The development of aloe vera gel as a stable and
practical pharmaceutical preparation became an important step in the effective
treatment of wounds. This study aimed to test the phytochemical content and
effectiveness of Aloe Vera Extract (Aloe Barbadensis Miller) in healing grade
II burns in wistar rats (Rattus norvegicus). Conducted with a pre-post-test
control group design approach in January 2024. Samples of aloe vera plants were
obtained from a traditional market in Medan City, North Sumatra. In this study,
20 Wistar rats were divided into 4 treatment groups. Variables observed
included topical formulations and wound healing processes in mice. The results
showed a significant difference in wound healing period between the treatment
group (Aloe Vera Ointment 25% and 50%) compared to the Control group, with a
value of p = 0.003. These findings support aloe vera's potential as an
effective therapeutic thanks to the anti-inflammatory and antioxidant
properties of compounds such as flavonoids and saponins. Therefore, Aloe Vera
Ointment can be considered as an effective option to improve the healing
process of burns.
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Pages:1-4
How to cite this article:
Wu Pingdong, Liena "Efficacy test of <i>Aloe Vera</i> ethanol extract ointment (Aloe Barbadensis Milleer) On healing grade Ii Burns in Wistar Rats". International Journal of Medical Science and Research, Vol 6, Issue 2, 2024, Pages 1-4
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