Background: Stroke is one of the most devastating neurological disease with dire complications. One of the complications of stroke is post stroke epilepsy. The mortality of post stroke epilepsy is higher (3, 4 % - 4%) compared to other complications of stroke. The Preffered treatment for post stroke epilepsy is monotherapy, which is effective in 88% of the case. Although effective, the current established treatment for post stroke epilepsy such as carbamazepine or lamotigrine shows higher side effects. Discussion: Gabapentin is one of the approved drugs for epilepsy. Although the mechanism of action is unknown, gabapentin is effective in treating epilepsy with patients receiving 900 mg/day dose and 1,800 mg/day dose stayed longer in the study compared to placebo. Gabapentin also shows lower side effect compared to establish treatment such as carbamazepine with gabapentin treated patient showed 60% adverse events and carbamazepine 84% adverse events. Conclusion: Gabapentin could be the potential drug for post stroke epilepsy which is safe, effective, and has lower side effects.