This particular research was carried out to evaluate in vitro anti-inflammatory activity of Electrohomeopathic medicine Angiotico - 2 (A-2) in Wistar rats. Literature study shows no scientific report has been available until date on the anti-inflammatory of A-2. Therefore the current analysis focuses to prove scientifically the anti-inflammatory activity of Electrohomeopathic medicine A-2. The anti-inflammatory property of A-2 was evaluated using carragenan induced mice oedema animal models of albino rats of either sex. The in vivo anti-inflammatory activity of Electrohomeopathic medicine A-2 showing potent anti-inflammatory properties as that compared to standard drug Ibuprofen.