Objectives: This present study was to evaluate the incidence, and compare the laproscopic cholecystectomy versus open cholecystectomy in gall bladder patients.

Methods: A total of 50 patients of gall bladder stone were enrolled in this study. Out of 50 patients, 35 patients were undergone for laproscopic cholecystectomy (LP) procedures and 15 patients were undergone open cholecystectomy (OC) procedures.

Results: Data was analysed by using IBM SPSS version 26 software. Chi-square and Mann-Whitney test were applied. P value was considered less than or equal to 0.05 for significant differences (p≤0.05).

Conclusions: Gall bladder stone was commonly seen in middle age group patients. Female was more preponderance than male. Guarding was the most common symptoms and nausea, vomiting, jaundice were second common symptoms. On ultrasonic findings, most of the patients had multiple stone. Operative time was significantly lesser in LC than OC. Wound infection was commonly seen in OC. On histopathological reports, chronic cholecystitis was commonly seen in gall bladder stone patients. Short duration in hospital stay and time taken to return to normal work were significantly lesser in LC than OC. Hence, LC is associated with less chance of wound infection and there is no risk of wound dehiscence. The degree of post-operative pain and its duration is less. The duration of hospital stay is less and patients can be discharged quickly from the hospital. Patients of LC group can resume their work earlier. So that, laproscopic cholecystectomy should be as the best choice procedure for gall bladder stone patients.